Symptomatic patients received additional event recording. The 7-day Holters at 12 months were evaluated for documented left atrial tachyarrhythmia recurrences, and each individual day with AF was categorized.
Results: At 12 months after the procedure, 21 of the 96 (22%) patients had AF on their 7-day Holter. In the patients with AF recurrence, there was an increase in sensitivity from 53% of a 1-day Holter up to 88% with 4-day Holter, and 100% of a 7-day
Holter. Monitoring with duration of less than 4 days resulted in significantly less detection of patients with AF compared to 7-day Holter.
Conclusions: A 4-day Holter at 12 months has an 88% sensitivity for arrhythmia detection, and appears to provide a sufficient CP-868596 mw monitoring time. Prolonging the monitoring time to 7 days does not significantly increase the yield. (PACE 2012; 35:164-169)”
“Background: Coronary heart disease (CHD) is typically associated with many cardiovascular risk factors (e.g., elevated blood pressure), low health-related quality of life, depression, anxiety and psychological stress. Expressive writing (EW) has shown beneficial effects on such variables in both people from the community and in patients DAPT supplier with a variety of chronic illnesses. However, no study to date has evaluated the physical and psychological effects of
the expressive writing procedure on coronary patients referred to cardiac rehabilitation (CR).
Methods: The clinical effectiveness of a 2-week disease-related
expressive writing procedure (writing about one’s deepest thoughts and feelings regarding the experience with heart disease) compared with the standard writing task (writing about one’s deepest thoughts and feelings about the most traumatic or negative event experienced in the life), a neutral writing condition (writing about the facts regarding heart disease and its treatment) and an empty control condition will be evaluated in a randomized controlled clinical trial (RCT) with repeated follow-up measurements at 3, 6 and 12 months after discharge from CR. The primary outcome is health-related quality of life (SF-12). Secondary outcome measures are depression (BDI-II), anxiety (BAI) and post-traumatic growth (PTGI). Furthermore, the study will explore the moderating ON-01910 nmr effects of coping styles, type D personality, perceived emotional support and participants’ evaluative ratings of the writing interventions on the main experimental effects in order to identify sub-groups of patients showing different results.
Discussion: The WRITTEN-HEART study aims to explore and expand the frontiers of the expressive writing research enterprise by investigating the feasibility, safety and clinical efficacy of brief and cost-effective expressive writing interventions in patients with CHD referred to CR.”
“Determining the forces that conserve amino acid positions in proteins across species is a fundamental pursuit of molecular evolution.