Therefore, the larger solvation that occurs in the carbonyl oxygen atom of the eq conformer is responsible for the observed and calculated decrease of the corresponding frequency. The X-ray single crystal analysis of 2 indicates that this compound adopts the most polar eq geometry in the solid. In fact, in order to obtain the largest energy gain, the molecules are arranged in the crystal in

a helical fashion due to dipole moment coupling along with C-H center dot center dot center dot O and C-H center dot center dot center dot pi(Ph) hydrogen bonds.”
“ObjectiveThis paper examines health reform which has been designed to improve cancer services across Western Australia. SettingWestern Australia is a large state divided into nine regions each with differing demographics. The diversity www.selleckchem.com/products/icg-001.html of the state and the distribution of the population over a large area of land create significant challenge in ensuring equality in service delivery. DesignA comparison

was conducted looking at cancer services in Western Australia pre-2005 and service delivery in 2014. A review of the partnership initiatives and programs provides a clear discussion on the need for coordination of care between service providers. Main OutcomeThe approach undertaken in Western Australia has seen an increase in the delivery of cancer services closer to the patient’s home as well as greater involvement of primary care professionals in cancer care. This work has resulted in demonstrated improvements in patient care and support. ConclusionServices for cancer patients need to be accessible AS1842856 order closer to home

with distance being an appreciable barrier to treatment access.A statewide approach needs to be developed to ensure all people have equitable access to service delivery.”
“BackgroundAlthough LY2835219 supplier influenza vaccination is an important component of antenatal care and is recommended and funded by the Australian government, vaccination uptake has been low. AimsThis study compared seasonal influenza vaccination uptake among pregnant Western Australian (WA) women and identified factors associated with vaccination uptake. Materials and MethodsAdult women who were pregnant during the 2012 and 2013 influenza vaccination seasons were selected at random and invited to complete a computer-assisted telephone interview survey about whether they received influenza vaccination during pregnancy. Data analyses were weighted to the age distribution of women of reproductive age in WA. Multivariate logistic regression was used to identify factors associated with vaccination uptake. ResultsBetween 2012 and 2013, the proportion of WA women whose antenatal care provider recommended influenza vaccination increased from 37.6 to 62.1% and vaccination uptake increased from 23.

Nineteen volunteers performed 12 series of 8 maximum CMJs. Changes in jump height between conditions and within the series were analysed. Jump heights differed between conditions (P smaller than 0.001), resulting in best performance with AF (32.04 +/- 7.11cm), followed by EF (31.21 +/- 6.67cm) and IF (30.77 +/- 6.87cm). Significantly different (P smaller than 0.001) within-series effects of higher jump heights at the end of the series in AF (+1.60%) and lower jump heights at the end of the series in EF (-1.79%) and IF (-1.68%)

were observed. Muscle activity did not differ between conditions. The differences between conditions and within the series provide evidence that AF leads to higher performance and better progression within one series than EF and IF. Consequently, AF seems to outperform EF and IF when maximising

jump height.”
“Objectives: A number of associations ML323 have been shown between early growth and later sex hormone levels in women, but less is known about this relationship in men. This selleck chemicals study investigated lifecourse predictors of sex hormones in men in the Newcastle Thousand Families birth cohort.\n\nMethods: The Newcastle Thousand Families Study is a prospective study initiated in 1947. At age 49-51 years, 574 study members returned detailed self-completion questionnaires and 412 attended for clinical examination, including 172 men in whom blood samples were taken. Estradiol, follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and sex hormone binding globulin (SHBG) were measured. Free testosterone concentrations were also calculated.\n\nResults: Social class at birth independently predicted FSH and LH, with higher levels with increasing socioeconomic disadvantage. SHBG was higher with increasing standardized birth weight

and lower with increasing contemporary body mass index (BMI). BMI also predicted LH, SHBG, and testosterone. None of the variables included within this analysis were significant predictors of estradiol. No other associations were seen with any of the variables included from across the lifecourse.\n\nConclusions: Our findings suggest that birth weight may be positively GSK1210151A Epigenetics inhibitor associated with SHBG and early socioeconomic status may be related to FSH and LH in men. These novel findings are independent of contemporary BMI. Given the links between sex hormones, SHBG and disease outcomes such as type II diabetes and osteoporosis, it is possible that sex hormones may play a mediating role in the associations between circumstances in early life and later risk of chronic disease. Am. J. Hum. Biol. 23:185-189, 2011. (C) 2010 Wiley-Liss, Inc.”
“The present study examined for the first time both the ocular and manual responses in a prediction motion (PM) task requiring participants to estimate time-to-contact (TTC) of an accelerating object.

The proposed new design of saturation pulse train can saturate effectively, and with this method first-pass myocardial perfusion imaging is feasible in humans at 7T. Magn

Reson Med 73:1450-1456, 2015. (c) 2014 The Authors. Magnetic Resonance in Medicine Published by Wiley Periodicals, Inc. on behalf of International Society of Medicine in Resonance.”
“OBJECTIVE. The objective of our study was to estimate the mortality benefit-to-risk ratio of pulmonary CT angiography (CTA) by setting (ambulatory [emergency department or outpatient] or inpatient), age, and sex.\n\nMATERIALS AND METHODS. A retrospective evaluation of 1424 consecutive pulmonary A-1331852 CTA examinations was performed and the following information was recorded: examination setting, patient age, patient sex, pulmonary CTA interpretation for pulmonary embolus (PE), and CT radiation exposure (dose-length product). We estimated mortality benefit of pulmonary CTA by multiplying the rate of positive pulmonary CTA examinations by published estimates of mortality of untreated PE in ambulatory and inpatient settings. We estimated the lifetime attributable LBH589 purchase risk of cancer mortality due to radiation from pulmonary CTA by calculating the estimated effective dose and using sex-specific polynomial equations derived from the Biological Effects of Ionizing Radiation VII report. We calculated benefit-to-risk ratios by dividing

the mortality benefit of preventing a fatal PE by the mortality risk of a radiation-induced cancer.\n\nRESULTS. Pulmonary CTA diagnosed PE in 188 of 1424 patients (13.2%). Both inpatients (101/723, 14.0%) and emergency department patients (74/509, 14.5%) had significantly higher rates of PE than outpatients

(13/192 [6.8%]). Males received significantly (p = 0.02451) higher radiation dose (9.7 mSv) than females (8.4 mSv), but males had a significantly (p < 0.0001) lower lifetime attributable risk of cancer mortality than females. Assuming an untreated PE mortality rate MRT67307 in vivo of 5% for ambulatory patients and 30% for inpatients, the benefit-to-risk ratio ranged from 25 for ambulatory patients to 187 for inpatients. Ambulatory women had the lowest benefit-to-risk ratio.\n\nCONCLUSION. The benefit-to-risk ratio of pulmonary CTA in patients with suspected PE ranges from 25 to 187 and can be increased by optimizing the radiation dose.”
“A type of pH-responsive nano multi-drug delivery systems (nano-MDDSs) with uniform particle size (100 +/- 13 nm) and excellent monodispersity was developed by in situ co-self-assembly among water-insoluble anti-cancer drug (doxorubicin, DOX), surfactant micelles (CTAB) as chemosensitiver and silicon species forming drugs/surfactant micelles-co-loaded mesoporous silica nanoparticles (drugs@micelles@MSNs or DOX@CTAB@MSNs) via a micelles-MSNs self-assembly mechanism.

\n\nMETHODS HUCs were obtained by bladder biopsy and cultured onto the luminal and abluminal surfaces of decellularized porcine small intestinal submucosa (SIS) and porcine urinary bladder matrix (UBM). In addition, HUCs selleck kinase inhibitor were cultured in optimal in vitro growth conditions and in their expected in vivo urine environment. The attachment, viability, and proliferative activity of HUCs were evaluated and compared using quantitative viability indicators and fluorescent markers for intracellular esterase activity and plasma membrane integrity.\n\nRESULTS The luminal and abluminal surfaces of the UBM demonstrated

significantly greater HUC viability and proliferative activity compared with the luminal and abluminal surfaces of the SIS grafts (P < .0001). Culture of HUCs in a simulated in vivo urine environment significantly affected cell viability (P < .0001). Proliferative activity was immeasurable on cell-seeded scaffolds that were cultured in a

urine environment after 48 hours of growth (P < .0001).\n\nCONCLUSIONS This is the first comparative report of UBM and SIS. Our results have demonstrated that UBM has significantly greater regenerative potential for HUCs compared with SIS. However, the perceived potential for extracellular matrixes in reconstructive urology might be limited by their inability to induce urothelial regeneration in a urine environment. UROLOGY 77: 1007.e1-1007.e7, 2011. (C) 2011 Elsevier Inc.”
“Objectives: To systematically review the literature Fludarabine mw on quality indicators (QIs) for evaluating trauma care, identify PLX4032 manufacturer QIs, map their definitions, and examine the evidence base in support of the QIs.\n\nData Sources: We searched MEDLINE, EMBASE, CINAHL, Cochrane Database of Systematic Reviews, Cochrane Database of Abstracts of Reviews of Effects, and Cochrane Central Register

of Controlled Trials from the earliest available date through January 14, 2009. To increase the sensitivity of the search, we also searched the grey literature and select journals by hand, reviewed reference lists to identify additional studies, and contacted experts in the field.\n\nStudy Selection and Data Extraction: We selected all articles that identified or proposed 1 or more QIs to evaluate the quality of care delivered to patients with major traumatic injuries. Minimum inclusion criteria were a description of 1 or more QIs designed to evaluate patients with major traumatic injuries (defined as multisystem injuries resulting in hospitalization or death) and focused on prehospital care, hospital care, posthospital care, or secondary injury prevention.\n\nData Synthesis: The literature search identified 6869 citations.

Mol Cancer Ther; 9(6); 1809-19. (C)2010 AACR.”
“Objective. Extensive association analyses including genome-wide association studies (GWAS) and powerful metaanalysis studies have identified a long list of loci associated with rheumatoid arthritis (RA) in very large populations, but most of them established statistical associations of genetic markers and RA only at the DNA level, without supporting evidence of functional

Ispinesib relevance. Our study serves as’ a trial to detect the functional mechanisms underlying associations for RA by searching publicly available datasets and results.\n\nMethods. Based on publicly available datasets and results, we performed integrative analyses (gene relationships across implicated loci analysis, differential gene expression analysis, and functional annotation clustering analysis) and combined them AZD0156 clinical trial with the expression quantitative trait locus (eQTL) results to dissect functional mechanisms underlying the associations for RA.\n\nResults. By searching 2 GWAS, Integrator and PheGenl, we selected 98 RA association results (p < 10(-5)). Among these associations, we found that 8 single-nucleotide polymorphisms (SNP; rs 1600249, rs2736340,

rs3093023, rs3093024, rs4810485, rs615672, rs660895, and rs9272219) serve as cis-effect regulators of the corresponding eQTL genes (BLK and CD4 in non-HLA region; CCR6, HLA-DQA1, and HLA-DQB1 in HLA region) that also were differentially expressed in RA-related cell groups. These 5 genes are closely related with immune response in function.\n\nConclusion. Our results showed the functional mechanisms underlying the associations of 8 SNP and the corresponding genes. This study is an example of mining publicly available datasets and results in validation of significant disease-association results. Using public data resources for integrative analyses

may provide insights into the molecular genetic mechanisms underlying human diseases.”
“J Clin Hypertens (Greenwich). 2012;00:0000 (c) 2012 Wiley Periodicals, Inc. The authors aim was to investigate the prognostic value of first-visit systolic and diastolic blood pressure (SBP/DBP) in hypertensive patients with stable coronary artery disease (sCAD) in conditions of contemporary daily clinical practice. From February CA3 1, 2000, to January 31, 2004, 690 consecutive hypertensive patients with sCAD (mean age 68 +/- 10 years, 65% male) were prospectively followed in the outpatient cardiology clinic for major events (acute coronary syndrome, revascularization, stroke, heart failure, or death) and associations with baseline SBP/DBP were investigated. At first visit, median SBP/SDP were 130/75 mm Hg (interquartile range, 2575; 120140/7080 mm Hg). After 25 months of follow-up (median), 19 patients died (2.8%); 10 from cardiovascular causes (1.5%), 87 patients experienced a coronary event (13%), and 130 patients (19%) a major event.

In female rats, the E1(4)-PRLR mRNA expression levels increased markedly during lactation compared with the diestrus state, whereas there was no increase in the E1(3)- and E1(5)-PRLR mRNA levels. The E1(4)-PRLR mRNA expression pattern was similar to that of the total PRLR mRNA. The PRL plasma concentration generally correlated with the E1(4)-PRLR mRNA expression levels in both sexes. These findings suggest that PRLR gene

expression in the choroid plexus is upregulated mainly via the transcriptional activation of the E1(4)-first PRT062607 cell line exon.”
“During cell cycle arrest caused by contact inhibition (CI), cells do not undergo senescence, thus resuming proliferation after replating. The mechanism of senescence avoidance during CI is unknown. Recently, it was demonstrated that the senescence program, namely conversion from cell cycle arrest to senescence (i.e., geroconversion), requires mammalian target of rapamycin (mTOR). Geroconversion can find more be suppressed by serum starvation, rapamycin, and hypoxia, which all inhibit mTOR. Here we demonstrate that CI, as evidenced by p27 induction

in normal cells, was associated with inhibition of the mTOR pathway. Furthermore, CI antagonized senescence caused by CDK inhibitors. Stimulation of mTOR in contact-inhibited cells favored senescence. In cancer cells lacking p27 induction and CI, mTOR was still inhibited in confluent culture as a result of conditioning of the medium. This inhibition of mTOR suppressed p21-induced senescence. Also, trapping of malignant cells among contact-inhibited normal cells antagonized p21-induced β-Nicotinamide molecular weight senescence. Thus, we identified two nonmutually exclusive mechanisms of mTOR inhibition in high cell density: (i) CI associated with p27 induction in normal cells and (ii) conditioning of the medium, especially in cancer cells. Both mechanisms can coincide in various proportions in various cells. Our work explains why CI is reversible and, most importantly, why cells avoid senescence in vivo, given that cells are contact-inhibited in the organism.”
“The aim of the study was to evaluate the seric

ions level and its relationship with Premenstrual Syndrome (PMS) symptoms in young women. Method: Ninety-three volunteers were monitored for three months. The nutritional status evaluation was based on BMI. Three “maps of daily symptoms” were used to investigate the frequency of the SPM symptoms. The biochemical evaluation was done in the first month in the luteal phase. The levels of sodium, potassium, calcium, magnesium were determined by colorimetric methods. The hemoglobin and hematocrit concentration were determined by conventional methods. Results: The symptoms like anxiety (1,13; 0,81; 0,66), edema (0,99; 0,51; e 0,22), depression (0,58; 0,36; 0,20) and mastalgia (0,56; 0,35; 0,09) were the most evident in the menstrual than luteal and follicular phase.

The platform has been tested with home-based rehabilitation and education programs for chronic obstructive pulmonary disease and diabetes. As part of our work, a risk assessment of privacy and security aspects has been performed, to reveal 8-Bromo-cAMP actual risks and to ensure adequate information security in this technical platform.\n\nMethods: Risk assessment was performed in an iterative manner during the development process. Thus, security solutions have been incorporated into the design from an early stage instead of being included as an add-on to a nearly completed system. We have adapted existing risk management methods to our own environment, thus creating

our own method. Our method conforms to ISO’s standard for information security risk management.\n\nResults: A total of approximately 50 threats and possible unwanted incidents were identified and analysed. Among the threats to the four information security aspects: confidentiality, integrity, availability, and quality; confidentiality threats were identified as most serious, with one threat given an unacceptable level of High risk. This is because health-related personal information is regarded as sensitive. Availability threats were analysed as low risk, as the aim of the home programmes is to provide education and rehabilitation services; not for use in acute situations or for continuous health monitoring.\n\nConclusions: Most of the identified threats are

applicable for healthcare services intended for patients or citizens in their selleck kinase inhibitor own homes. Confidentiality risks in home are different from in a more controlled environment such as a hospital; and electronic equipment located in private homes and communicating via Internet, is more exposed to unauthorised access. By implementing the proposed measures, it has been possible to design a home-based service which ensures the necessary level of information security and privacy.”
“The self-assembly Selleck Staurosporine of head-tail type block copolymers composed of polyamidoamine dendron head block and poly(L-lysine) (PLL) tail block was studied using a light scattering technique and transmission electron microscopy. A PLL tail block in

a head-tail type block copolymer exhibits a coil-to-helix transition as a result of the change in solvent quality from water to methanol. When the PLL tail block takes a helical conformation in high methanol content, the resulting head-tail type block copolymer has a defined three-dimensional structure like that of a protein molecule. Self-assemblies of such block copolymers having a totally fixed molecular shape spontaneously form polymersome-like self-assemblies with an extremely narrow size distribution through converging to a thermodynamically stable assembling state. (C) 2009 Wiley Periodicals, Inc. J Polyrn Sci Part A: Polym Chem 47: 1217-1223, 2009″
“High temperature steam electrolysis (HTSE) is one of the most promising ways for hydrogen mass production.

Other CCs showing signet-ring morphology present negativity for mucins and correspond to a fixation artefact.”
“Fe-x(CoNi)(1-x) (x = 0.14, 0.20, 0.25) ternary alloy nanoparticles were fabricated by a self-catalyzed reduction method at a low temperature. The investigation of static magnetic properties revealed both saturation magnetization and coercive force enhanced with increasing Fe content. By dispersing alloy nanoparticles into paraffin matrix homogeneously, the electromagnetic properties of them were investigated ACY-738 Epigenetics inhibitor experimentally and the electromagnetic

absorption performances were calculated according to transmission line theory. Significant dielectric relaxation was found in the low Fe content sample, which is dominant in dielectric loss. The magnetic loss was attributed to natural resonance and the resonance peaks’ shift to high frequency region with increasing Fe content. The enhanced electromagnetic absorption performances were obtained by adjusting Fe content to balance selleckchem electromagnetic parameters, because the electromagnetic parameters can be varied by structural and magnetic properties. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3556762]“
“Complex mixtures of contaminants with potential adverse effects on human health and wildlife are found in the environment and in the food chain. These mixtures include numerous anthropogenic compounds

of various origins and structures, which may behave as endocrine disruptors. Mixture’s complexity is further enhanced by biotic and abiotic transformations. It is therefore necessary to develop new strategies allowing the identification of the structure of known, as well as unknown, nuclear receptor (NR) ligands present in complex matrices. We explored the possibility to use NR-based affinity

columns to characterize the presence of bioactive molecules in environmental complex mixtures. Estrogen receptor alpha (ER alpha)-based affinity columns were used to trap and purify estrogenic substances present in surface sediment samples collected in AP26113 research buy a French river under mixed anthropogenic pressure. We combined biological, biochemical and analytical approaches to characterize the structure of ligands retained on columns and demonstrate the presence of known active molecules such as bisphenol A and octylphenol, but also of unexpected ER alpha ligands (n-butylparaben, hydroxyl-methyl-benzofuranone). High resolution mass spectrometry results demonstrate that ER alpha affinity columns can be used for the isolation, purification and identification of known as well as unknown estrogenic contaminants present in complex matrices.”
“The in-plane magnetic anisotropy was studied for a quaternary alloy ferromagnetic semiconductor [(InyGa1-y)(1-x)Mn-x]As thin film with x = 0.12 and y = 0.54 grown on an InP(001) substrate using planar Hall effect measurements. The present [(In0.54Ga0.46)(0.88)Mn-0.

T-cell proliferation was determined

by the extent of carboxyfluorescein diacetate succinimidyl ester (CFSE) dye dilution on culture day 5 of PBMCs in the presence of antigen (SEB, PPD, CMVpp65, selleck chemicals llc GagA and GagD). Samples were analyzed on a FACS Calibur flow cytometer and flow data was analyzed using FlowJo and GraphPad.\n\nResults: Overall, CD4 T-cell proliferation on stimulation with SEB, PPD, CMVpp65, Gag A and Gag D. antigens, was lower among suboptimal than optimal responders; this was significant for SEB (CD4+ p=0.003; CD8+p=0.048) and PPD antigens (CD8+ p=0.038). Among suboptimal responders, T-cell proliferation decreased with increasing immune activation (Negative correlation; slope = -0.13 +/–0.11) but not among optimal responders.\n\nConclusion: T-cell immune activation and exhaustion were associated with poor proliferation among suboptimal responders to HAART despite sustained viral suppression. We recommend studies to further selleck inhibitor understand the mechanisms leading to impaired T-cell function among suboptimal

responders as well as the potential role of immune modulation in optimizing CD4 count and functional recovery after HAART.”
“Study design: A prospective study. Objectives: To evaluate the effect of the surgery to reconstruct thoracic breathing in patients with high cervical spinal cord injury (CSCI). Setting: China Rehabilitation Research Center, Beijing, China. Methods: The posterior ribs (from the fifth to the eighth) were suspended on the inferior angle of the scapula on each side using titanium

cables, as well as muscles and myofascial tissue in the subscapular area. After the surgery, the patients were trained for synchronous contraction of the trapezius and diaphragm muscles, and electromyography (EMG) was performed to evaluate the synchronization. The clinical symptoms and pulmonary function were assessed within 1 week before surgery and at 2, 12 and 24 postoperative weeks. Results: Six patients with complete high CSCI received rib suspension surgery 84 +/- 26.7 days after spinal cord injury. Before the surgery, all of the patients presented with weakened cough, retention of respiratory Proteasome activity secretions and dyspnea, while these symptoms alleviated postoperatively. The vital capacity (VC) was enhanced to be 1680 +/- 282 ml at 2 weeks after the surgery, compared with 1085 +/- 92 ml (P = 0.013). The EMG showed a synchronous muscle electrical activity between the trapezius muscles and diaphragm during deep breaths. Conclusion: The rib suspension surgery partially restored the thoracic breathing of the patients with high CSCI, thereby improving VC, cough and expectoration.”
“Purpose: To evaluate the efficacy of long scleral tunnel technique used in Ahmed glaucoma valve (AGV) implantation in preventing tube exposure through conjunctiva.

4-fold induction after 24 h. Angiotensin II-mediated miRNA-21 expression resulted

in biologically active miRNA-21, determined using a fusion mRNA reporter system carrying miRNA-21 Semaxanib clinical trial target sequences in its 3′ untranslated region. Up-regulation of miRNA-21 intracellular levels increased aldosterone secretion but not cortisol. Elevation of miRNA-21 levels also increased cell proliferation in H295R cells. In summary, miRNA-21 is an endogenously expressed miRNA in human adrenal cells. miRNA-21 expression is up-regulated by angiotensin II, and its overexpression caused an increase in aldosterone secretion and cell proliferation. Alterations in miRNA-21 expression levels or function may be involved in dysregulation of angiotensin II signaling and abnormal aldosterone secretion by adrenal glands in humans.”
“BACKGROUND: The purpose of this study was to test a novel, dual tumour vascular endothelial cell (VEC)- and tumour cell-targeting factor VII-targeted Sn(IV) chlorin e6 photodynamic therapy (fVII-tPDT) by targeting a receptor tissue factor (TF) as an alternative treatment for chemoresistant Selleckchem DMXAA breast cancer using a multidrug resistant (MDR) breast cancer line MCF-7/MDR.\n\nMETHODS: The

TF expression by the MCF-7/MDR breast cancer cells and tumour VECs in MCF-7/MDR tumours from mice was determined separately by flow cytometry and immunohistochemistry using anti-human or anti-murine TF antibodies. The efficacy of fVII-tPDT was tested in vitro and in vivo and was compared with non-targeted PDT for treatment of chemoresistant breast cancer. The in vitro efficacy was determined by a non-clonogenic assay using crystal violet staining for monolayers, and apoptosis and necrosis were assayed to elucidate the underlying mechanisms. The in vivo efficacy of fVII-tPDT was determined in

a nude mouse model of subcutaneous MCF-7/MDR tumour xenograft by measuring tumour volume.\n\nRESULTS: To our knowledge, this is the first presentation showing that TF was expressed on tumour VECs in chemoresistant breast tumours from mice. The in vitro efficacy of fVII-tPDT was 12-fold stronger than that of ntPDT for MCF-7/MDR cancer cells, and the mechanism of action involved induction of apoptosis and necrosis. BMS-777607 order Moreover, fVII-tPDT was effective and safe for the treatment of chemoresistant breast tumours in the nude mouse model.\n\nCONCLUSIONS: We conclude that fVII-tPDT is effective and safe for the treatment of chemoresistant breast cancer, presumably by simultaneously targeting both the tumour neovasculature and chemoresistant cancer cells. Thus, this dual-targeting fVII-tPDT could also have therapeutic potential for the treatment of other chemoresistant cancers. British Journal of Cancer (2011) 104, 1401-1409. doi:10.1038/bjc.2011.88 www.bjcancer.com Published online 22 March 2011 (C) 2011 Cancer Research UK”
“BACKGROUND: Early postoperative bowel obstruction is associated with considerable morbidity and mortality after colorectal surgery.