FEMS Microbiol Lett 1999, 169–174. 29. Okeke IN, Borneman JA, Shin S, Mellies JL, Quinn LE, Kaper JB: Comparative sequence analysis of the plasmid-encoded regulator of enteropathogenic Escherichia coli strains. Infect Immun 2001, 69:5553–5564.PubMedCrossRef 30. Fernandes R, Ramos S, Rassi V, Blake P, Gomes T: Use of plasmid profiles to differentiate strains within specific serotypes of classical enteropathogenic Escherichia coli . Braz J Med Biol Res 1992, 25:667–672.PubMed 31. Lim YS, Ngan CC, Tay L: Enteropathogenic Escherichia coli as a cause of diarrhoea among children in Singapore. J Trop Med Hyg 1992, 95:339–342.PubMed 32. Vila J, Vargas M, Casals C,

Urassa H, Mshinda H, Selleckchem GF120918 Schellemberg D, Gascon J: Antimicrobial resistance of diarrheagenic Escherichia coli isolated from children under the age of 5 years from Ifakara, Tanzania. Antimicrob Agents Chemother Selleckchem MAPK inhibitor 1999, 43:3022–3024.PubMed 33. Moyenuddin M, Wachsmuth IK, Moseley SL, Bopp CA, Blake PA: Serotype, antimicrobial resistance, and adherence properties of Escherichia coli strains associated with outbreaks of diarrheal illness in children in the United States.

J Clin Microbiol 1989, 27:2234–2239.PubMed 34. Gross RJ, Ward LR, Threlfall EJ, King H, Rowe B: Drugresistance among infantile enteropathogenic Escherichia coli strains isolated in the United Kingdom. Br Med J (Clin Res Ed) 1982, 285:472–473.CrossRef 35. Slocombe B, Sutherland R: Transferable antibioticresistance in enteropathogenic Escherichia coli between 1948 and 1968. Antimicrob Agents Chemother 1973, 4:459–466.PubMed 36. Lévesque C, Piché L, Larose C, Roy PH: PCR mapping of integrons reveals several novel combinations

of resistance genes. Antimicrob Agents Chemother 1995, 39:185–191.PubMed 37. Johnson TJ, Wannemuehler YM, Johnson SJ, Logue CM, White DG, Doetkott C, Nolan LK: Plasmid replicon typing of commensal and pathogenic Escherichia coli isolates. Appl Environ Microbiol SB-3CT 2007, 73:1976–1983.PubMedCrossRef 38. Berquo LS, Barros AJ, Lima RC, Bertoldi AD: Use of drugs to treat respiratory tract infections in the community. Rev Saude Publica 2004, 38:358–364.PubMed 39. Berquo LS, Barros AJ, Lima RC, Bertoldi AD: Use of antimicrobial drugs in an urban population. Rev Saude Publica 2004, 38:239–246.PubMed 40. National LY3039478 nmr Committee for Clinical Laboratory Standards: Performance standards for antimicrobial disk susceptibility tests. 8th edition. National Committee for Clinical Laboratory Standards, Villanova, PA; 2003. Authors’ contributions ICAS and INO conceived the study and wrote the paper. TBS and KRSA performed the laboratory studies. All authors read and approved the final manuscript.”
“Background The dramatic rise in antibiotic-resistant pathogens has renewed efforts to identify, develop and redesign antibiotics.