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“Background Intracranial aneurysms are reported to occur in 1–10% of the population and are associated with considerable morbidity and mortality following rupture.[1–3] The Paclitaxel mouse estimated rate of aneurysm rupture ranges between 0–2% per year, and is dependent on factors such as family history and the size and location of the aneurysm; small aneurysms (<10 mm in diameter) in arteries in the front of the brain carry a lower risk than those in arteries at the rear of the brain.[3–5] Since its introduction in clinical practice in the 1990s, endovascular coiling for the treatment of cerebral aneurysms
has gained widespread use.[4,6] Noninvasive coil embolization for an unruptured aneurysm is relatively safe compared with invasive surgical treatment such as aneurysmal clipping.[3,4] The structure of the platinum coil adjacent to the intimal surface of the artery facilitates the reconstruction of the parent artery by stimulating endothelial growth that promotes stasis, platelet adhesion, clotting, thrombosis, and occlusion of the aneurysm, resulting in blood flow remodeling. Improvements in techniques and management in recent years have facilitated a reduction in procedural risks associated with coil embolization for unruptured cerebral aneurysms;[6,8] however, acute and delayed thromboembolic events, including stroke and transient ischemic attacks (TIA), remain the most common clinical complications[6,10] with reported incidence rates of 4–28%.